Automated Diabetes Management with the Help of Pain-Free Skin Patch

Automated Diabetes Management with the Help of Pain Free Skin Patch

Researchers have developed a pain-free skin patch, which contains soluble compounds that responds to blood chemistry for automatic glucose management.

Type-2 diabetes progressively lowers the body’s ability to make or use insulin. Diabetes can result into vascular and nerve damage throughout the body if left untreated with devastating impacts on the eyes, kidneys, and heart. According to Continuous Glucose Monitoring (CGM) Market report published by Coherent market Insights, People suffering from type 2 diabetes need continuous monitoring of blood glucose level. A finger prick before mealtimes and an insulin injection is an uncomfortable but necessary routine. Type-1 diabetes is characterized by inability of body to secrete insulin.

Researchers from National Institute of Biomedical Imaging and Bioengineering revealed on December 26, 2017, that they have developed a biochemically formulated patch of dissolvable micro needles for the treatment of type 2 diabetes. The study was published in the journal Nature Communications. The biochemical formula of mineralized compounds in the patch responds to blood chemistry to manage glucose automatically. Study was performed over mice model, which showed that the chemicals interact in the bloodstream to regulate blood sugar for days at a time. “A weekly micro needle patch application would also be less complicated and painful than routines that require frequent blood testing,” said Richard Leapman of National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of National Institutes of Health (NIH).

Alginate is the base material of this experiment patch. It is a gum-like natural substance extracted from brown algae. It is mixed with therapeutic agents and poured into a micro needle form to make the patch. The team infused the alginate with a formula of biochemical particles that stimulates the insulin production of body when required and limits stimulation when normal blood sugar concentration is achieved. The alternate therapy approach developed by NIBIB researchers may eventually make management of Type-2 diabetes more convenient as compared to conventional methods.

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