Caffeine Affects People Based on their Genes
Researchers reveal that athletic enhancement after drinking coffee depends upon genetic makeup, according to a new study published on March 21, 2018.
A team of researchers studied the genetics of caffeine metabolism, revealing that athletes with a particular variant of gene exhibit enhancements in their endurance performance after swallowing caffeine.
However, those with different variants of that gene may perform worse if they first have caffeine.
They explain the reason for different people responding differently to the effects of caffeine. Some have difficulty sleeping, while other get jitters and no sleep disruptions.
A gene called CYP1A2, is known to control the expression of an enzyme that affects the breakdown and clearance of caffeine from the body.
One variation of the helps in quick metabolism of caffeine. While those who have two copies of this variant, offers them with a quick jolt, quickly disappearing.
About 40 percent of people are thought to be moderate metabolizers, with the remaining 10 percent being genetically slow metabolizers. The drug was experimented on, which was found to produce cardiac effects on slow metabolizers. While others might benefit from caffeine.
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