Calcium and Vitamin Supplements might be Unable to Guard against Hip Fractures
Supplements containing calcium and vitamin D or both were found to be unable in protecting against bone and hip fracture in older adults.
Calcium and vitamin D supplements are mainly recommended for older people to prevent fractures in those with osteoporosis. Research conducted regarding particular topic have shown mixed conclusion about an association between supplements and fracture risk. According to the Vitamins Market report published by Coherent Market Insights, vitamins and calcium are required in trace amount for growth and development of an individual. Deficiency of vitamins of may lead to osteoporosis, osteomalacia, colorectal cancer, and thyroid deficiency. Around 51,145 adults above the age of 50 residing in communities such as nursing homes and residential care facilities were participated in 33 randomized clinical trials, which compared the use of supplement such as calcium, vitamin D or both with placebo or no treatment and new fractures.
The study was conducted by Jia-Guo Zhao, M.D at Tianjin Hospital, Tianjin, China. The study was carried out as meta-analysis, which combined the results of multiple studies identified in a systematic review and quantitatively summarized the overall association between the same exposure, which included supplements containing calcium, vitamin D or both and fracture outcomes across all studies.
Results of the study showed that supplements were not associated with less risk for new fractures, irrespective of the dose, sex of the patient, and their fracture history, calcium intake in their diet or baseline vitamin D blood concentrations. However, limitations to this study was some trials included in the analysis were unable to test baseline vitamin D blood concentration for all participants. The results for some subgroups might have been different if all individuals were screened for the test. Findings of the study do not support routine use of supplements containing calcium, vitamin D or both by older adults for prevention of fracture.
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