CE Mark Cleared X-Ray Pill for Screening Colon Cancer in Europe
European regulators CE Mark approved newly developed pill that emits X-rays to image the colon on January 18, 2018.
Conventional colonoscopies used for screening colon cancer can be invasive, require diet and laxatives that leave patients feeling empty and exhausted. The C-Scan System from Check-Cap features ingestible pill that has an X-ray source, a positioning system, computing components, and a battery. The patient have to swallows a contrast agent and wear special sensors attached to the skin where colon is located. The capsule moves through the sensors to pick up imaging and location data that it transmits without requirement for laxatives and sedation.
The pill operates with two separate X-ray phenomena. One involves shooting the X-rays into the swallowed contrast agent, which fluoresces its own X-rays in return. This makes it and the contents with more readily visible. The other phenomenon is called Compton scattering, which is exhibited when X-rays interact with electrons in the tissues of the colon wall and which results in some of the X-rays coming back to the pill. Combining these two readings produces a novel view inside the colon that has the potential to identify lesions that would need a closer inspection.
According to X Ray Detectors Market report published by Coherent Market Insights, X-rays have been in use for non-invasive imaging of biological matters by passing high resolution radiations. X-Rays have wide range of applications such as structural imaging of bones, cavities in soft tissues, and metal implants pre and post operational comparisons. This imaging technology has the advantage of using ultra-low dose radiation due to the fact that the imaging target objects are within very close proximity to the capsule, hence a very low x-ray flux is required to obtain sufficient signal-to-noise ratio and good image quality.
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