Empty Capsules Market: Release latest trends & Industry Vision
Manufacturers can mix active pharmaceutical ingredients according to their need and can prepare a dosage form according to the requirement with the help of empty capsules. Capsules offer an easy way to administer drugs as these are easy to disintegrate, easy to swallow, and have faster dissolution times than other oral solid dosage forms. Advancement in technology such as sustained release dosage and extended release dosage in capsules, to achieve the required effects is expected to be factor for growth of the market. Advantages offered by capsules over tablets such as improved palatability and freedom to administer solid as well as semisolid drugs is driving growth of the empty capsules market. Furthermore, patients with kidney or liver problems can take the supplements through vegetarian capsules with no side effects as excretion of additional protein (present in gelatin capsules) from the body is difficult. These factors are expected to impact the empty capsules market over the forecast period.
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Shell component and composition are important factors while manufacturing empty capsules. Gelatin or a non-gelatin polymeric material such as hypromellose, water, starch, and plasticizer is used in manufacturing hard or soft gelatin capsule shells. Different coatings can be used on shells in order to achieve the desired therapeutic action once the capsule is administered to the patient. For instance, enteric coated capsules are designed to release the drug in the intestine. Moreover, sustained release capsules are designed to release the drug ingredients slowly over a longer duration of time. Capsules can also be manufactured to achieve local effect, while bypassing the first pass metabolism such as rectal capsule, which are inserted into the rectal cavity. However, requirement of a capsule filling machine is important as filling each capsule by hand is time consuming.
Introduction of different types of materials for capsule manufacturing is supporting growth of the empty capsules market
Gelatin has widely been used material for empty capsules and is obtained from natural sources such as bovine gelatin and porcine gelatin. Two types of capsules can be manufactured using gelatin such as hard gelatin capsules and soft gelatin capsules. However, these capsules have limitations owing to the nature of gelatin as certain compounds cannot be mixed with gelatin such as highly water soluble compounds. Introduction of other compatible materials has widened the scope of applications for these products. For instance, introduction of non-gelatin capsules, which are synthetic (hydroxypropylmethyl cellulose) as well as vegetarian capsules has aided in growth of the market. Vegetarian capsules such as pullulan are made from tapioca plant and offers several advantage over gelatin capsules. Vegetarian capsules cause lesser allergies as compared to other forms. Moreover, people with hypersensitivity to cow and bovine products can consume vegetarian capsules. Thus, demand for vegetarian capsules is expected to increase significantly over the forecast period.
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However, requirement of an industrial grade capsule filling machine is important as filling each capsule by hand is time consuming. Moreover, limitations with gelatin capsules such as restrictions on drug compatibilities, and difficulty for kidney and liver disease patient in excretion of additional protein content in gelatin capsules is expected to impact the growth of the empty capsules market.
Some players operating in the global empty capsules market are ACG Associated Capsules Pvt. Ltd., Capsugel, Inc., CapsCanada Corporation, Medicaps Ltd., Qualicaps, Inc., JC Biological Technology Co., Patheon, Inc., Roxlor LLC, and Sunil Healthcare Ltd.
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