Fecal Pills Prove to be More Effective than Invasive Treatments for C. difficile Infection
Dr. Thomas Louie, clinical professor at the Cumming School of Medicine pioneered the development of the FMT pill, according to an article published in Science Daily in December 2017.
According to Anti-bacterial Drugs Market reports published by Coherent Market Insights, Major pharmaceutical industries and research institutes are developing next-generation antibacterial drugs to effectively prevent intestinal infections but Recurrent C. difficile infection, is known to be effectively treated by capsules containing frozen fecal bacteria from a healthy donor, which can be taken orally, showing a 96 percent success rate. The concept might seems putting-off for many, however is a blessing for those suffering severely from intestinal infections. It is equally effective as receiving a transplant by colonoscopy. These pills are made by processing feces until only the bacteria remains, further encapsulating the bacteria into three layers of gelatin capsule. These pills have no scent or taste and are a one-shot deal, not a continuing treatment.
Different gut bacteria reside in the human gut, which together help the digestive and immune systems to function properly. However, when harmful infections require treatment with antibiotics, the very same antibiotics can disrupt the healthy balance of the gut bacteria, allowing microorganisms such as C. difficile to cause illness.
“Capsules have numerous advantages over colonoscopy. They are non-invasive, they’re less expensive, they don’t have any of the risks associated with sedation and they can be administered in a doctor’s office,” said Dr. Dina Kao, an associate professor with the University of Alberta’s Faculty of Medicine and Dentistry and lead author of the study
The study, revealed that although the taste and smell of the pill was not unpleasant, the high number of pills required to be taken, amounted up to 40 capsules within an hour. This resulted in long hours of sleep and intense starving on awaking. However, this continued for two days, for patients, after which their health drastically improved, destroying the C. difficile infection.
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