Flatscope Lens-Free Fluorescent Microscope to Assist in Deep Body Imaging

Researchers from Rice University developed a thin fluorescent microscope called as FlatScope, which can image details at micrometer scale while focusing on a volume of a few cubic millimeters

The study was published in Science Advances in March 2018. The novel lens-free microscope is small enough to sit on a fingertip and capable of micrometer resolution over a volume of several cubic millimeters. FlatScope reduces the need of conventional microscopes in which arrays of lenses can either gather less light from a large field of view or gather more light from a smaller field. The researchers claim that FlatScope can be potentially used as implantable endoscope and a large-area imager or a flexible microscope.

The a microscope doesn’t use any lenses due to which it can be placed at the tips of endoscopes for long term monitoring of brain activity.  Moreover, the size of the field view can be increased by increasing the size of the sensor. The sensor is a conventional complementary metal–oxide–semiconductor (CMOS) detector. “In the case of a megapixel camera, that computational problem requires a matrix of a million times a million elements,” said Robinson, researcher involved in study. “It’s an incredibly big matrix. But because we break it down through this pattern of rows and columns, our matrix is just 1 million elements.”

The device operates on amplitude mask, which allows production of high quality images. The sensor captures the light that comes through the mask to develop image. For final image, the device uses algorithm that records the amplitude mask and converts the imaging data into a high resolution picture. It has ability to produce a focused image from distances, which can help in developing 3D movies of objects within a volume of a few cubic millimeters. However, researchers believe that further research is required for using FlatScope in bright-field, dark-field, and reflected-light microscopy.

You may be interested

New Study Reports Odds of Living to 110-Plus Level out After the Age of 105
Healthcare
Healthcare

New Study Reports Odds of Living to 110-Plus Level out After the Age of 105

Mohit Joshi - November 16, 2018

Researchers from University of California – Berkeley report that chances of reaching the age of 110 are increased once a person survives for 105 years. A research…

Researchers Discover New Toxic Gene in Cholera Bacteria
Healthcare
Healthcare

Researchers Discover New Toxic Gene in Cholera Bacteria

Mohit Joshi - November 15, 2018

Researchers from Umea University discovered structure and function of an unknown Vibrio toxin in Cholera bacteria The bacterium Vibrio cholera is the main cause of bacterial infectious…

Protein Assays Market Growth Analysis,Opportunities Forecasts Report till 2026
Business
Business

Protein Assays Market Growth Analysis,Opportunities Forecasts Report till 2026

Albert R - November 14, 2018

“Protein Assays Market is expected to have a highly positive outlook for the next five years 2018–2026 according to a recently released Protein Assays Market research report.…

Most from this category