Growth of New Skin Saves Child’s Life

Growth-of-New-Skin-Saves-Child’s-Life

Doctors successfully grow skin to cover 80 percent of the body of a patient suffering from a genetic disease thus, saving his life.

Scientists have long attempted to grow new human skin by means of genetic engineering, however, have not been successful at growing even half a square feet of skin.

According to a study published in the journal Nature, in November 2017, doctors at the Ruhr University collaborated with Michele de Luca, director of the Center for Regenerative Medicine at the University of Modena and Reggio Emilia, Italy, to engineer skin as an attempt to save the life a young boy suffering from a disease called junctional epidermolysis bullosa (JEB).

JEB is a genetic disorder in which skin mutates causing blister easily and making the patient more susceptible to develop cancer. The boy in the study lost over two-thirds of skin due to development of a bacterial infection leaving him bright red and raw. He was admitted Germany’s Children’s Hospital at Ruhr University.

The team along with de Luca extracted stem cells and immature cells from the boy, as these possess the ability to develop into other types of cells and continue growing. To prevent mutation, they delivered a harmless virus into the normal version of gene and inserted it into the skin cells. The engineered skin along with the stem cells was then used to grow new skin in the laboratory.

Attempts resulted in healthy growth of skin, which was finally grafted back onto the kid’s body. The kid was hospitalized for over eight months, however his recovery has helped him perform activities that any normal kid would, with ease.

The study reveals that a few living stem cells have the ability to grow and maintain skin for a long time. This has been a genetic breakthrough, in which doctors have been able to cover over nine feet of a patient’s body, that was earlier not possible. The patient has been able to live a healthy and normal life even two years from the surgery. This newly discovered skin engineering technique creates potential application for future skin grafting, which could possibly save the lives of many.

You may be interested

Smart Nanotechnology Enlivens Wooden Ships and Artifacts
Business
Business

Smart Nanotechnology Enlivens Wooden Ships and Artifacts

Mohit Joshi - January 28, 2019

Scientists developed an innovative approach using ‘smart’ nanocomposites to conserve 16th-century British warship, the Mary Rose, and its artifacts. Shipwrecks are preserved in sediments under cold water,…

Researchers Discovered New Properties of Ferroelectric Crystal
Business
Business

Researchers Discovered New Properties of Ferroelectric Crystal

Mohit Joshi - January 25, 2019

Researchers discovered new properties of ferroelectric crystal, according to a study published on July 10, 2018. This study was conducted by a team of researchers from China.…

Researchers Develop Novel Antibody to Knockdown of Protein in Vertebrates
Healthcare
Healthcare

Researchers Develop Novel Antibody to Knockdown of Protein in Vertebrates

Mohit Joshi - January 24, 2019

Researchers from Technische Universität Dresden developed a synthetic antibody that improves functional analysis of proteins. A research led by Dr. Jörg Mansfeld of the Biotechnology Center of…

Most from this category