Low Fitness Level can Elevate Risk of Dementia

Low Fitness Level can Elevate Risk of Dementia

Researchers from UT Southwestern’s O’Donnell Brain Institute reported that daily exercise improves neural health reducing the risk of cognitive disorders.

Researchers reported fitness level of an individual represents mental health. The findings of the study report that poor fitness level is reduces the white matter in brain. White matter refers to the millions of nerve fibers that nerve cells use to communicate across the brain. Deterioration of these results into declining cognitive abilities of person leading to diseases that affect memory such as dementia and Alzheimer’s disease.

Results of the study showed that older patients who were at a high risk of Alzheimer’s disease showed early signs of mild cognitive impairment. The results of the study concluded that lower fitness level was associated with reduced white matter, which, in turn was related to poor brain function.

The O’Donnell Brain Institute is also leading a five-year national clinical trial, which is focused on examining the correlation between fitness levels and dementia. Around 600 adults at high risk of developing Alzheimer’s disease were involved in the study. The trial involves six medical centers across the country. The researcher are also focused on finding the effect of daily aerobic exercise maintained high blood pressure and cholesterol levels with medication on brain function.

This research supports the hypothesis that improving people’s fitness may improve their brain health and slow down the aging process.” Dr Kan Ding, Assistant Professor in Neurology & Neurotherapeutics at UT Southwestern’s O’Donnell Brain Institute.

Teams at the institute are engaged in developing tests for the early detection of dementia risk and pathways for lowering the spread of toxic proteins such as beta-amyloid and tau, which destroy certain nerve cells in the brain.

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