Stem Cell Therapy for Blindness

Stem Cell Therapy for Blindness

Pfizer in collaboration with University College London (UCL) has developed PF 5206388, an intraocular implant consisting of a single layer of retinal pigment epithelium (RPE) cells. It consists of a polymer framework carrying stem cells, designed to be set into the eye, according to Biotecnika on August 2, 2017.

This therapy first treated a patient in 2015, however, Pfizer has recently updated the therapy. It has abandoned four of its early-stage clinical projects, including the stem cell therapy. Pfizer derived cells from the embryonic stem cells and designed them for patients with a disorder that causes blindness.

In a clinical trial conducted by the specialists at Moorfields Eye Hospital, 10 patients were to be treated of a disease called wet age-related macular degeneration (AMD). Surgeons inserted a specially engineered patch behind the retina of the patients to deliver the stem cells. The operation was successful on all the 10 participants.

PF-06282999 was created for treating acute coronary syndrome (ACS) and belonging to the myeloperoxidase (MPO) inhibitor class, which is a group known to have potential to treat a range of illnesses such as cardiovascular, inflammatory, and neurodegenerative diseases.

Sources report that Pfizer is planning to dump another applicant treating cardiovascular illnesses – monoglyceride lipase (MGLL) inhibitor PF-06818883. The inhibitor was being developed as a treatment for intracerebral hemorrhage, and glucagon receptor blocker PF-06293620 for type 2 diabetes was also discarded. Pfizer, in its second-quarter 2017 report said that it spent around US$ 3.49 billion on R&D during the first half of the year.

You may be interested

Dental Implants Market to Develop Rapidly by 2018 – 2026
Healthcare
Healthcare

Dental Implants Market to Develop Rapidly by 2018 – 2026

Albert R - August 21, 2018

Dental Implants Market report 2018-2026 focuses on the major drivers and restraints for the key players. These research report also provides granular analysis of the market share,…

Latest Evolution of Geriatric Care Services Market Analysis 2026
Healthcare
Healthcare

Latest Evolution of Geriatric Care Services Market Analysis 2026

Albert R - August 21, 2018

Geriatric Care Services Market report 2018-2026 focuses on the major drivers and restraints for the key players. These research report also provides granular analysis of the market…

Custom LASIK Surgery Market – Latest Developments
Healthcare
Healthcare

Custom LASIK Surgery Market – Latest Developments

Albert R - August 21, 2018

Custom LASIK Surgery Market report 2018-2026 focuses on the major drivers and restraints for the key players. These research report also provides granular analysis of the market…

Most from this category