Study Reveals A Novel Way to Synthesize Antioxidant Substances

Study Reveals A Novel Way to Synthesize Antioxidant Substances

Scientists from Tomsk Polytechnic University with colleagues from USA and Japan have proposed a novel way to synthesize new organic substances. The study was published in Chemistry European Journal on December 22, 2017.

Researchers were able to carry out separation of water molecules with the help of synthesized substances called arylbenziodoxaboroles. As a result, the scientists synthesized a number of novel phenolic substances that possess high biological and antioxidant activity, which can be used for drug development in near future. According to the scientists, ordinary water as a green solvent is a highly interesting medium for conducting chemical reactions that allows substances to manifest new properties.

Benziodoxaborole is a precursor that presents a chemical building block that is used to create other substances. Researchers performed reaction in water at room temperature and obtained a highly reactive intermediate aryne, resulting in novel phenolic substances to be further obtained. They possess a high biological and antioxidant activity. It is available and easily regenerated. Aryne intermediates are usually obtained either with hard irradiation or using organic solvents.

These elements helped to break the bond between carbon and hydrogen in molecules to create a new carbon-carbon bond and thereby obtain new promising substances. According to Green Chemicals published by Coherent Market Insights, synthesis of new materials such as antioxidants. The study lines up with the concept of green chemistry focused on the reduction of the negative impact of chemical industry on the environment.

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