Adenovirus Diagnostic Testing Market Perspective by Comprehensive Analysis Growth Prediction to 2026
Adenovirus Diagnostic Testing Market – Driver
Adenoviruses are associated with a variety of nonspecific manifestations and clinical syndromes, thus diagnosis based upon clinical criteria alone is challenging. Diagnosis is most accurate when the infection shows outbreak symptoms or individuals show serious disease manifestations. Validation of adenovirus infection is essential for identifying the most appropriate treatment to establish a prognosis and initiate infection control measures by using correct antiviral agents, thus making diagnosis of these viruses a vital procedure. This in turn, is expected to augment growth of the adenovirus diagnostic testing market. Generally, there are two types of adenoviruses namely, Type 4 and Type 7 that caused severe outbreaks of respiratory illness, especially among military recruits. Thus, adenovirus vaccine, containing Type 4 and Type 7, is thus approved for military personnel aged 17 to 50 years from 1971, to protect them against the illness caused by these two viruses. In the recent past, adenovirus infections were diagnose by cell culture, as the virus replicates efficiently in cell cultures. Monoclonal antibodies are also used to detect infected cells using direct fluorescence antibody assays. Amplification and detection of adenovirus DNA by polymerase chain reaction methods are also gaining popularity as laboratory methods to determine adenovirus infection. The rapid detection and quantitation of adenovirus DNA, especially by a sensitive PCR technique is expected to aid in the diagnosis and treatment monitoring of adenovirus infections, particularly in immunocompromised patients. This in turn, is expected to boost growth of the adenovirus diagnostic testing market during the forecast period.
Moreover, growing research and development of technologies for use in the diagnosis of acute respiratory infections of viral etiology is expected to fuel market growth. For instance, in 2014, DiaSorin launched its sixth LIAISON test for the qualitative detection of adenovirus in stool samples in markets outside the U.S. and the U.K., the test is an addition to the 5 most important tests of the stool testing panel, already available in the market (C. Difficile toxin A&B, C. Difficile GDH, Helicobacter Pylori, EHEC, and Rotavirus).
Adenovirus is one of the DNA viruses that are considered to be a major cause of febrile illness, primarily among children. Individuals and Infants with weak immune systems, cardiac disease or chronic respiratory problems are at higher risk of developing adenovirus infection, however, most infections are not severe. Adenovirus is a communicable infection, as it is an air-borne diseases and can spread from infected person to others by coughing and sneezing, and close contact such as shaking or touching hands. Adenovirus can cause pneumonia, acute respiratory disease, epidemic kerato-conjunctivitis, acute follicular conjunctivitis, gastroenteritis, and cystitis. Among infants, pharyngeal-conjunctival and pharyngitis fever are commonly caused by Adenovirus. In 2016, a study conducted by Barcelona Center for International Health Research and University of Barcelona, on children suffering from pneumonia, suggests that adenovirus is the second-most common respiratory virus causing pneumonia. Some adenoviruses can also spread through the infected person’s stools, for instance, during diaper changing.
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Adenovirus can also spread through water such as swimming pools, however, this is less common. Adenovirus infections can be usually diagnose by molecular methods or can be detected with polymerase chain reaction (PCR), serology, antigen detection or viral culture. Others emerging technologies such as liposomes, monoclonal antibodies, chromatography, flow cytometry, and gel micro droplets are also of vital use in diagnosis of adenovirus infection.
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