Cystinosis Treatment Market Perspective by Comprehensive Analysis Growth Prediction to 2026

Cystinosis is a condition characterized by accumulation of the cystine (amino acid) within cells. High amount of cystine damages cells and often forms crystals that can damage tissues and organs. The eyes and kidneys are mainly susceptible to damage; however, the pancreas, muscles, testes, and thyroid can also be affected. Cystinosis is categorized into three different types; nephropathic, non-nephropathic or ocular, and intermediate cystinosis. Nephropathic (infantile) cystinosis is the most severe and common form of cystinosis. Renal Fanconi syndrome and growth failure are usually the first noticeable symptoms of this disorder.

To get detailed table of content (ToC), please click: https://www.coherentmarketinsights.com/ongoing-insight/toc/1660

Intermediate cystinosis is characterized by symptoms similar to that of nephropathic cystinosis. However, these symptoms are not prominent till age of 8-20 years. Non-nephropathic cystinosis generally affects adults during middle age with eye disorder. Kidney disease does not occur in these individuals. Individuals with non-nephropathic cystinosis develop photophobia due to cystine crystal accumulation in the eyes.

All three types of cystinosis occur due to mutations in the CTNS gene. Mutations in CTNS gene cause deficiency of a transporter protein called cystinosin. Cystinosin normally moves cystine out of the lysosomes, which are compartments in the cell that recycle and digest materials. Defects in cystinosin, allows accumulation of cystine and forms crystals in the lysosomes and its buildup damages cells in the eyes and kidneys. According to National Institutes of Health (NIH), cystinosis affects around 1 in 100,000 to 200,000 infants globally. Cystinosis is the most common cause of renal Fanconi syndrome in children and accounts for nearly 5% of all childhood cases of kidney failure. Fanconi syndrome, a rare disorder of kidney tubule function results in excess amounts of potassium, uric acid, glucose, phosphates, bicarbonate, and certain amino acids excreted in the urine. Cysteine depleting therapy can significantly reduce cysteine levels inside the cells. It improves growth and decreases kidney damage in children. Symptomatic therapy treats renal Fanconi syndrome with a high intake of electrolytes and fluids to prevent extreme body dehydration. Sodium bicarbonate, potassium, sodium citrate, and magnesium can help to keep standard electrolyte stability. Acetyl cholinesterase (ACE) inhibitors are also used sometimes to limit the growth of the renal disease.

Click To Continue Reading on Cystinosis Treatment Market

You may be interested

Business

Global Metallic Couplings Market by Type, Deployment, Industry, Approach, and Geography- Forecast to 2026

Albert R - December 14, 2018

According to the new market research report on "Global Metallic Couplings Market Report 2018 - 2026” covers there Product Type, Region Coverage, Application or End-user, Industry Insights…

Business

Essential Insights to Know About the Global Mining Lubricant Market Report 2018

Albert R - December 14, 2018

According to the new market research report on "Global Mining Lubricant Market Report 2018 - 2026” covers there Product Type, Region Coverage, Application or End-user, Industry Insights…

Business

Global Metformin Hydrochloride Market – Statistics, Facts and Forecast to 2026

Albert R - December 14, 2018

According to the new market research report on "Global Metformin Hydrochloride Market Report 2018 - 2026” covers there Product Type, Region Coverage, Application or End-user, Industry Insights…

Most from this category