New Drug Could Reverse Effects of Excessive Drinking
New drug named as tandospirone can effectively aid in reversing harmful effects caused by heavy smoking on brain.
According to the research published in the journal Scientific Reports, Tandospirone drug selectively acts on a serotonin receptor. The researchers also showed that the drug was effective in inhibiting anxiety-like behaviors associated with heavy alcohol intake accompanied by a significant decrease in binge-like alcohol intake.
As a part of study, mice was supplemented with drug for two weeks. Reversed effects was observed after15 weeks of binge-like alcohol consumption on neurogenesis – the ability of the brain to grow and replace neurons. This is the first time tandospirone has been shown to reverse the deficit in brain neurogenesis induced by heavy alcohol consumption. “This is a novel discovery that tandospirone can reverse the deficit in neurogenesis caused by alcohol,” said Professor Selena Bartlett from the Queensland University of Technology in Australia. “This opens the way to look at if neurogenesis is associated with other substance-abuse deficits, such as in memory and learning, and whether this compound can reverse these,” she said.
According to the researchers, this drug is relatively new and available only in China and Japan. It is commonly used in this region and it is proved to be to be highly effective in treating general anxiety with limited adverse effects. The researchers are working on developing strategies for alcohol abuse and addiction, which is characterized by extended periods of heavy alcohol use, binges and abstinence, and anxiety and depression resulting into relapse. “This is not just another drug that shows promise in helping to reduce binge drinking,” Bartlett said. “While it could possibly have that effect, it might be able to help reboot the brain and reverse the deficits the alcohol abuse causes,” she said.
You may be interested
Closed MRI Systems Market – Latest Advancements & Market Outlook 2018 to 2026Pareesh Phulkar - May 21, 2018
Magnetic resonance imaging (MRI) is a non-invasive medical test that uses powerful magnetic field, radio waves, and a computer to produce detailed virtual image of internal organs…
Rising number of surgical procedures coupled with increasing trauma cases to foster global hemostasis & tissue sealing agents marketAlbert R - May 19, 2018
Hemostasis is a physiological processes, which maintains fluidity of blood by preventing blood loss from body. Hemostasis is characterized by clot formation by activating the natural coagulation…
Synovial Sarcoma Treatment Market Regional InsightsAlbert R - May 19, 2018
Synovial sarcoma consists of abnormal growth of soft-tissue. Synovial sarcoma is a rare type of cancer and is more prevalent in teenagers and young adults. Synovial sarcoma…