Researchers Developed New Technique to Predict Relapse in Blood Cancer Patients
Researchers have developed a technique which helps in determining if children suffering acute lymphoblastic leukemia would relapse after the treatment, according to a study conducted on March 5, 2018.
The main aim of developing this technique is to identify the patients suffering from acute lymphoblastic leukemia who needs another approach to the treatment of cancer. This can also lead to the development of new drugs that target the deadly cancer cells. This cancer is diagnosed in 3,000 American children per year. Even though chemotherapy drugs can cure majority of the cases, a relapse is observed in 10-12 percent of patients.
Studies conducted earlier suggests that relapse of cancer occurs due to the cells that are resistant to the treatment, which are present from the initial stage of the disease. Bone marrow samples from 60 patients were tested using mass cytometry. Researchers organized the data to spot the cells that are problematic.
Kara Davis, assistant professor of pediatric hematology said, “Every patient has vastly different features to their cancer, and we had to ask, ‘is there any common thread between them?’” Finally, the team came up with a solution, which was to compare leukemic cells with the normal cells. By combining new methods with the existing methods, better results were obtained.
Davis said, “We do not understand the mechanisms by which malignant cells from the pro-B2 and pre-B1 stages of development resist treatment.” Researchers are planning to use this method in more number of patients to find out if this method can be used to predict the relapse of other cancers. This method would be beneficial for patients who are at risk of relapse.
This new technique would help in increasing the growth of leukemia therapeutics market, as detailed in the leukemia therapeutics market report published by Coherent Market Insights.
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