Turmeric Extract Based Eye Drops to Treat Glaucoma at Early Stage

coherentnews

Chemical called as curcumin derived from turmeric has shown to reduce glaucoma-associated retinal cell damage, according to the study published in the journal Scientific Reports in July 2018

Glaucoma is a group of eye conditions that can result in to blindness by destroying retinal cells. New study reported that orally-ingested curcumin – a chemical derived from the spice turmeric – can be used for treatment of glaucoma. However, challenge associated with oral administration of curcumin orally is that it is insoluble and subsequently enter the bloodstream easily. Moreover, patients will have to take around 24 tablets a day to observe positive effect, which may lead to cause unwanted gastrointestinal side effects.

To overcome this challenge, scientists at University College London and Imperial College London developed a liquid medication, which delivers the chemical directly to the eye in the form of drops. The solution carries the curcumin within a surfactant combined with a stabilizing agent, both of which are already used in other eye products. This approach reportedly not only allows the medication to deliver a higher concentration of curcumin than is possible using other eye drops currently in development, but it also increases the chemical’s solubility by a factor of nearly 400,000.

As a part of the study, the researchers administered the drops twice a day for three weeks to rats suffering from ongoing retinal ganglion cell loss. Furthermore, it was compared to a group of untreated rats with the same condition. As a result, it was observed that the treated animals experienced a significant reduction in cell loss without side effects such as eye irritation or inflammation. Researchers believe that the medication can be used to effectively treat glaucoma in humans and to better diagnose Alzheimer’s disease – curcumin causes Alzheimer’s-related amyloid plaque deposits in patients’ retinas to light up, allowing the disease to be detected.

 

You may be interested

Smart Nanotechnology Enlivens Wooden Ships and Artifacts
Business
Business

Smart Nanotechnology Enlivens Wooden Ships and Artifacts

Mohit Joshi - January 28, 2019

Scientists developed an innovative approach using ‘smart’ nanocomposites to conserve 16th-century British warship, the Mary Rose, and its artifacts. Shipwrecks are preserved in sediments under cold water,…

Researchers Discovered New Properties of Ferroelectric Crystal
Business
Business

Researchers Discovered New Properties of Ferroelectric Crystal

Mohit Joshi - January 25, 2019

Researchers discovered new properties of ferroelectric crystal, according to a study published on July 10, 2018. This study was conducted by a team of researchers from China.…

Researchers Develop Novel Antibody to Knockdown of Protein in Vertebrates
Healthcare
Healthcare

Researchers Develop Novel Antibody to Knockdown of Protein in Vertebrates

Mohit Joshi - January 24, 2019

Researchers from Technische Universität Dresden developed a synthetic antibody that improves functional analysis of proteins. A research led by Dr. Jörg Mansfeld of the Biotechnology Center of…

Most from this category